Susceptibility to Plasmodium falciparum Malaria: Influence of Combined Polymorphisms of IgG3 Gm Allotypes and Fc Gamma Receptors IIA, IIIA, and IIIB

Susceptibility to Plasmodium falciparum Malaria: Influence of Combined Polymorphisms of IgG3 Gm Allotypes and Fc Gamma Receptors IIA, IIIA, and IIIB

The binding of immunoglobulin (Ig) to Fc gamma receptors (FcgR) at the immune cell surface is an important step to initiate immunological defense against malaria. However, polymorphisms in receptors and/or constant regions of the IgG heavy chains may modulate this binding. Here, we investigated whet...

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Bibliographic Details
Main Authors: Abdou Khadre Dit Jadir Fall, Celia Dechavanne, Audrey Sabbagh, Evelyne Guitard, Jacqueline Milet, André Garcia, Jean-Michel Dugoujon, David Courtin, Florence Migot-Nabias
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
malaria
IgG polymorphism
Gm allotypes
Fc gamma receptor
Benin
generalized multifactor dimensionality reduction
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.608016/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.608016/full

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