Translational Dysregulation in Cancer: Molecular Insights and Potential Clinical Applications in Biomarker Development

Although transcript levels have been traditionally used as a surrogate measure of gene expression, it is increasingly recognized that the latter is extensively and dynamically modulated at the level of translation (messenger RNA to protein). Over the recent years, significant progress has been made...

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Bibliographic Details
Main Authors: Christos Vaklavas, Scott W. Blume, William E. Grizzle
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00158/full