Structural Analysis of Crystalline R(+)-α-Lipoic Acid-α-cyclodextrin Complex Based on Microscopic and Spectroscopic Studies

Structural Analysis of Crystalline R(+)-α-Lipoic Acid-α-cyclodextrin Complex Based on Microscopic and Spectroscopic Studies

R(+)-α-lipoic acid (RALA) is a naturally-occurring substance, and its protein-bound form plays significant role in the energy metabolism in the mitochondria. RALA is vulnerable to a variety of physical stimuli, including heat and UV light, which prompted us to study the stability of its complexes w...

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Bibliographic Details
Main Authors: Naoko Ikuta, Takatsugu Endo, Shota Hosomi, Keita Setou, Shiori Tanaka, Noriko Ogawa, Hiromitsu Yamamoto, Tomoyuki Mizukami, Shoji Arai, Masayuki Okuno, Kenji Takahashi, Keiji Terao, Seiichi Matsugo
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:International Journal of Molecular Sciences
Subjects:
cyclodextrin
lipoic acid
ATR/FT-IR
microscopic Raman
solid-state NMR
Online Access:http://www.mdpi.com/1422-0067/16/10/24614

Internet

http://www.mdpi.com/1422-0067/16/10/24614

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