Humanized Mice in Dengue Research: A Comparison with Other Mouse Models

Humanized Mice in Dengue Research: A Comparison with Other Mouse Models

Dengue virus (DENV) is an arbovirus of the Flaviviridae family and is an enveloped virion containing a positive sense single-stranded RNA genome. DENV causes dengue fever (DF) which is characterized by an undifferentiated syndrome accompanied by fever, fatigue, dizziness, muscle aches, and in severe...

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Bibliographic Details
Main Authors: Carolina Coronel-Ruiz, Hernando Gutiérrez-Barbosa, Sandra Medina-Moreno, Myriam L. Velandia-Romero, Joel V. Chua, Jaime E. Castellanos, Juan C. Zapata
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Vaccines
Subjects:
denv
dengue mouse models
humanized mice
immune response
pathogenesis
vaccine
drug development
Online Access:https://www.mdpi.com/2076-393X/8/1/39

Internet

https://www.mdpi.com/2076-393X/8/1/39

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