Effect of the cancer specific shorter form of human 6-phosphofructo-1-kinase on the metabolism of the yeast Saccharomyces cerevisiae

Effect of the cancer specific shorter form of human 6-phosphofructo-1-kinase on the metabolism of the yeast Saccharomyces cerevisiae

Abstract Background At first glance, there appears to be a high degree of similarity between the metabolism of yeast (the Crabtree effect) and human cancer cells (the Warburg effect). At the root of both effects is accelerated metabolic flow through glycolysis which leads to overflows of ethanol and...

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Bibliographic Details
Main Authors: Darjan Andrejc, Alenka Možir, Matic Legiša
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Biotechnology
Subjects:
Deregulated glycolysis
Saccharomyces cerevisiae
6-phosphofructokinase
Cancer metabolism
Posttranslational modification
Online Access:http://link.springer.com/article/10.1186/s12896-017-0362-5

Internet

http://link.springer.com/article/10.1186/s12896-017-0362-5

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