Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors
<p>Abstract</p> <p>Background</p> <p>Assays of multiple tumor samples frequently reveal recurrent genomic aberrations, including point mutations and copy-number alterations, that affect individual genes. Analyses that extend beyond single genes are often restricted to e...
Main Authors: | Aldape Kenneth D, Sulman Erik P, Settle Stephen H, Miller Christopher A, Milosavljevic Aleksandar |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-04-01
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Series: | BMC Medical Genomics |
Online Access: | http://www.biomedcentral.com/1755-8794/4/34 |
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