Real-Time Quaking-Induced Conversion Detection of Bovine Spongiform Encephalopathy Prions in a Subclinical Steer

Bovine spongiform encephalopathy (BSE) belongs to a group of fatal prion diseases that result from the misfolding of the cellular prion protein (PrPC) into a pathogenic form (PrPSc) that accumulates in the brain. In vitro assays such as serial protein misfolding amplification and real-time quaking-i...

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Bibliographic Details
Main Authors: Soyoun Hwang, M. Heather West Greenlee, Anne Balkema-Buschmann, Martin H. Groschup, Eric M. Nicholson, Justin J. Greenlee
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Veterinary Science
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fvets.2017.00242/full