Antiobesity action of ɛ-polylysine, a potent inhibitor of pancreatic lipase
In vitro, ɛ-polylysine (EPL) strongly inhibited the hydrolysis of trioleoylglycerol emulsified with phosphatidylcholine (PC) and taurocholate by either pancreatic lipase or carboxylester lipase. The EPL concentration required for 50% inhibition of pancreatic lipase, 0.12 μM, was eight times lower th...
Main Authors: | Takahiro Tsujita, Hiroe Takaichi, Takeshi Takaku, Shigeyuki Aoyama, Jun Hiraki |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2006-08-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520331709 |
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