Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts.

Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts.

There are currently no reliable approaches for correctly identifying which patients with major depressive disorder (MDD) will respond well to antidepressant therapy. However, recent genetic advances suggest that Polygenic Risk Scores (PRS) could allow MDD patients to be stratified for antidepressant...

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Bibliographic Details
Main Authors: Joey Ward, Nicholas Graham, Rona J Strawbridge, Amy Ferguson, Gregory Jenkins, Wenan Chen, Karen Hodgson, Mark Frye, Richard Weinshilboum, Rudolf Uher, Cathryn M Lewis, Joanna Biernacka, Daniel J Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0203896

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https://doi.org/10.1371/journal.pone.0203896

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