Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges.

DNA helicases are ubiquitous enzymes that unwind DNA in an ATP-dependent and directionally specific manner. Unwinding of double-stranded DNA is essential for the processes of DNA repair, recombination, transcription, and DNA replication. Five human DNA helicases sharing sequence similarity with the...

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Bibliographic Details
Main Authors: Sudha Sharma, Robert M Brosh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2111050?pdf=render