Ischemia-reperfusion injury in a rat microvascular skin free flap model: A histological, genetic, and blood flow study.

Ischemia reperfusion injury is associated with tissue damage and inflammation, and is one of the main factors causing flap failure in reconstructive microsurgery. Although ischemia-reperfusion (I/R) injury is a well-studied aspect of flap survival, its biological mechanisms remain to be elucidated....

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Bibliographic Details
Main Authors: Alberto Ballestín, Javier G Casado, Elena Abellán, F Javier Vela, Verónica Álvarez, Alejandra Usón, Esther López, Federica Marinaro, Rebeca Blázquez, Francisco Miguel Sánchez-Margallo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209624