β-Lactam Exposure Triggers Reactive Oxygen Species Formation in Enterococcus faecalis via the Respiratory Chain Component DMK

Summary: Whereas the primary actions of β-lactams are well characterized, their downstream effects are less well understood. Although their targets are extracellular, β-lactams stimulate respiration in Escherichia coli leading to increased intracellular accumulation of reactive oxygen species (ROS)....

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Bibliographic Details
Main Authors: Loïc Léger, Aurélie Budin-Verneuil, Margherita Cacaci, Abdellah Benachour, Axel Hartke, Nicolas Verneuil
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719314020