Co-administration of lipopolysaccharide and d-galactosamine induces genotoxicity in mouse liver

Abstract The acute liver injury (ALI) and hepatic fibrosis caused by the co-treatment of lipopolysaccharide (LPS)/d-galactosamine (D-GalN) have been extensively studied. However, whether LPS/D-GalN are genotoxic has been left unknown. In this study, male mice were divided into eight groups with eigh...

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Bibliographic Details
Main Authors: Wenjing Dong, Erqun Song, Yang Song
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81383-5