The GluN3 subunit regulates ion selectivity within native N-methyl-d-aspartate receptors

The GluN3 subunit regulates ion selectivity within native N-methyl-d-aspartate receptors

Glutamatergic N-methyl-d-aspartate receptors (NMDARs) are heterotetrameric proteins whose subunits are derived from three gene families, GRIN1 (codes for GluN1), GRIN2 (GluN2) and GRIN3 (GluN3). In addition to providing binding sites for glutamate and the co-agonist glycine, these subunits in their...

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Bibliographic Details
Main Authors: Stephen Beesley, Thomas Sullenberger, Sanjay S. Kumar
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:IBRO Reports
Subjects:
Triheteromeric NMDA receptors
GluN3
Ion selectivity
Entorhinal cortex
Somatosensory cortex
Ion-substitution experiments
Online Access:http://www.sciencedirect.com/science/article/pii/S2451830120300327

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http://www.sciencedirect.com/science/article/pii/S2451830120300327

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