Regulation of microsomal triglyceride transfer protein mRNA expression by endotoxin and cytokines

We studied the effect of endotoxin (LPS), and cytokines (TNF, IL-1, and IL-6) on hepatic microsomal triglyceride transfer protein (MTP) mRNA levels in vivo in Syrian hamsters and in vitro in HepG2 cells. LPS, interleukin-1 (IL-1), and to a lesser extent tumor necrosis factor (TNF) significantly decr...

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Bibliographic Details
Main Authors:	Miguel Navasa, David A. Gordon, Narayanan Hariharan, Haris Jamil, Judy K. Shigenaga, Arthur Moser, Walter Fiers, Allan Pollock, Carl Grunfeld, Kenneth R. Feingold
Format:	Article
Language:	English
Published:	Elsevier 1998-06-01
Series:	Journal of Lipid Research
Subjects:	tumor necrosis factor interleukins apolipoprotein B hepatic nuclear factor-1 activating protein-1
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520325463

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http://www.sciencedirect.com/science/article/pii/S0022227520325463

Regulation of microsomal triglyceride transfer protein mRNA expression by endotoxin and cytokines

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