Shaping the Nascent Ribosome: AAA-ATPases in Eukaryotic Ribosome Biogenesis

Shaping the Nascent Ribosome: AAA-ATPases in Eukaryotic Ribosome Biogenesis

AAA-ATPases are molecular engines evolutionarily optimized for the remodeling of proteins and macromolecular assemblies. Three AAA-ATPases are currently known to be involved in the remodeling of the eukaryotic ribosome, a megadalton range ribonucleoprotein complex responsible for the translation of...

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Bibliographic Details
Main Authors: Michael Prattes, Yu-Hua Lo, Helmut Bergler, Robin E. Stanley
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Biomolecules
Subjects:
aaa-atpases
ribosome biogenesis
rix7/nvl2
rea1/mdn1
drg1/spata5
substrate processing
cryo-em
small molecular weight inhibitors
Online Access:https://www.mdpi.com/2218-273X/9/11/715

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https://www.mdpi.com/2218-273X/9/11/715

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