In vitro and in vivo inhibition of rabies virus replication by RNA interference

In vitro and in vivo inhibition of rabies virus replication by RNA interference

Rabies is a zoonotic disease that affects all mammals and leads to more than 55,000 human deaths every year, caused by rabies virus (RABV) (Mononegavirales: Rhabdoviridae: Lyssavirus). Currently, human rabies treatment is based on the Milwaukee Protocol which consists on the induction of coma and ma...

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Bibliographic Details
Main Authors: Ekaterina A. Durymanova Ono, Keila Iamamoto, Juliana G. Castilho, Pedro Carnieli Jr., Rafael de Novaes Oliveira, Samira M. Achkar, Maria L. Carrieri, Ivanete Kotait, Paulo E. Brandão
Format: Article
Language:English
Published: Sociedade Brasileira de Microbiologia 2013-09-01
Series:Brazilian Journal of Microbiology
Subjects:
rabies
RNA interference
siRNAs
antiviral
treatment
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000300034&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000300034&lng=en&tlng=en

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