Improved Synthesis of Phosphoramidite-Protected <i>N</i><sup>6</sup>-Methyladenosine via BOP-Mediated S<sub>N</sub>Ar Reaction
<i>N</i><sup>6</sup>-methyladenosine(m<sup>6</sup>A) is the most abundant modification in mRNA. Studies on proteins that introduce and bind m<sup>6</sup>A require the efficient synthesis of oligonucleotides containing m<sup>6</sup>A. We rep...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-12-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/1/147 |