Synthesis, Radiolabelling and In Vitro Characterization of the Gallium-68-, Yttrium-90- and Lutetium-177-Labelled PSMA Ligand, CHX-A''-DTPA-DUPA-Pep

Synthesis, Radiolabelling and In Vitro Characterization of the Gallium-68-, Yttrium-90- and Lutetium-177-Labelled PSMA Ligand, CHX-A''-DTPA-DUPA-Pep

Since prostate-specific membrane antigen (PSMA) has been identified as a diagnostic target for prostate cancer, many urea-based small PSMA-targeting molecules were developed. First, the clinical application of these Ga-68 labelled compounds in positron emission tomography (PET) showed their diagnost...

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Bibliographic Details
Main Authors: Benjamin Baur, Christoph Solbach, Elena Andreolli, Gordon Winter, Hans-Jürgen Machulla, Sven N. Reske
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Pharmaceuticals
Subjects:
PSMA
prostate-specific membrane antigen
PET
positron emission tomography
prostate cancer
DUPA
Ga-68
Y-90
Lu-177
radionuclide therapy
Online Access:http://www.mdpi.com/1424-8247/7/5/517

Internet

http://www.mdpi.com/1424-8247/7/5/517

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