The Pharmacogenetics of Cytochrome P450 2C19 Enzymes - Effects on Clopidogrel and Proton Pump Inhibitors

BACKGROUND: Cytochrome P450 (CYP) enzymes play important roles in human, including drug metabolism. CYP2 is the largest family of human CYP, with its sequence comprising almost one third of all CYP sequences, and responsible for the metabolism of approximately 2% of clinically administrated drugs. O...

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Bibliographic Details
Main Authors: Yusmiati Yusmiati, Dewi Muliaty
Format: Article
Language:English
Published: Secretariat of The Indonesian Biomedical Journal 2014-04-01
Series:Indonesian Biomedical Journal
Online Access:http://inabj.org/index.php/ibj/article/view/41