Pigment Epithelium-Derived Factor (PEDF) is a Determinant of Stem Cell Fate: Lessons from an Ultra-Rare Disease

PEDF is a secreted glycoprotein that is widely expressed by multiple organs. Numerous functional contributions have been attributed to PEDF with antiangiogenic, antitumor, anti-inflammatory, and neurotrophic properties among the most prominent. The discovery that null mutations in the PEDF gene resu...

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Bibliographic Details
Main Authors: Usman Sagheer, Jingjing Gong, Chuhan Chung
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Journal of Developmental Biology
Subjects:
Online Access:http://www.mdpi.com/2221-3759/3/4/112