l-3,4-Dihydroxyphenylalanine induces ptosis through a GPR143-independent mechanism in mice

Through its conversion to dopamine by aromatic l-amino acid decarboxylase (AADC), l-3,4-dihydroxyphenylalanine (l-DOPA) replenishes depleted brain dopamine in Parkinson's disease patients. We recently identified GPR143 as a candidate receptor for l-DOPA. In this study, we investigated the behav...

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Bibliographic Details
Main Authors: Suguru Ueda, Daiki Masukawa, Motokazu Koga, Yoshio Goshima
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861316301128