MicroRNA-Mediated Direct Reprogramming of Human Adult Fibroblasts Toward Cardiac Phenotype

MicroRNA-Mediated Direct Reprogramming of Human Adult Fibroblasts Toward Cardiac Phenotype

Modulation of microRNA expression holds the promise to achieve direct reprogramming of fibroblasts into cardiomyocyte-like cells as a new strategy for myocardial regeneration after ischemic heart disease. Previous reports have shown that murine fibroblasts can be directly reprogrammed into induced c...

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Bibliographic Details
Main Authors: C. Paoletti, C. Divieto, G. Tarricone, F. Di Meglio, D. Nurzynska, V. Chiono
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
cardiac fibroblasts
direct reprogramming
cardiomyocytes
microRNAs
digital droplet PCR (ddPCR)
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00529/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00529/full

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