Evolutionary engineering improves tolerance for medium-chain alcohols in Saccharomyces cerevisiae

Abstract Background Yeast-based chemical production is an environmentally friendly alternative to petroleum-based production or processes that involve harsh chemicals. However, many potential alcohol biofuels, such as n-butanol, isobutanol and n-hexanol, are toxic to production organisms, lowering t...

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Bibliographic Details
Main Authors: Stephanie A. Davis López, Douglas Andrew Griffith, Brian Choi, Jamie H. D. Cate, Danielle Tullman-Ercek
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Biotechnology for Biofuels
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13068-018-1089-9