Protocols for Visually Guided Navigation Assessment of Efficacy of Retina-Directed Cell or Gene Therapy in Canines

There has been marked progress in recent years in developing gene delivery approaches for the treatment of inherited blinding diseases. Many of the proof-of-concept studies have utilized rodent models of retinal degeneration. In those models, tests of visual function include a modified water maze sw...

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Bibliographic Details
Main Authors: Jean Bennett, Puya Aravand, Pavitra S. Ramachandran, Ivan Schpylchak, Nicholas T. Phelps, Sergei Nikonov
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Neuroscience
Subjects:
dog
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00215/full