Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis

Targeting virulence rather than bacterial growth is less likely to select for antibiotic resistance, but many possible targets function in both processes. Here, the authors reconstruct a genome-scale metabolic network ofP. aeruginosastrain PA14 and update that of strain PAO1, which, together with mu...

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Bibliographic Details
Main Authors: Jennifer A. Bartell, Anna S. Blazier, Phillip Yen, Juliane C. Thøgersen, Lars Jelsbak, Joanna B. Goldberg, Jason A. Papin
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14631