Characterization of the male ApcMin/+ mouse as a hypogonadism model related to cancer cachexia

Summary Cancer cachexia, the unintentional loss of lean body mass, is associated with decreased quality of life and poor patient survival. Hypogonadism, involving a reduction in circulating testosterone, is associated with the cachectic condition. At this time there is a very limited understanding o...

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Bibliographic Details
Main Authors: James P. White, Melissa J. Puppa, Aditi Narsale, James A. Carson
Format: Article
Language:English
Published: The Company of Biologists 2013-11-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/12/1346