Bach1 Induces Endothelial Cell Apoptosis and Cell-Cycle Arrest through ROS Generation

The transcription factor BTB and CNC homology 1 (Bach1) regulates genes involved in the oxidative stress response and cell-cycle progression. We have recently shown that Bach1 impairs cell proliferation and promotes apoptosis in cultured endothelial cells (ECs), but the underlying mechanisms are lar...

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Bibliographic Details
Main Authors: Xinhong Wang, Junxu Liu, Li Jiang, Xiangxiang Wei, Cong Niu, Rui Wang, Jianyi Zhang, Dan Meng, Kang Yao
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/6234043