TiO2 nanoparticles can selectively bind CXCL8 impacting on neutrophil chemotaxis

The interaction between TiO2 nanoparticles (NPs) and inflammatory cytokines, including CXCL8, a clinically relevant pro-inflammatory chemokine was investigated. TiO2 is present in tissues adjacent to failing implanted Ti (titanium) devices. TiO2 NPs were shown to bind to CXCL8 in vitro, causing pert...

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Bibliographic Details
Main Authors: J Batt, M Milward, I Chapple, M Grant, H Roberts, O Addison
Format: Article
Language:English
Published: AO Research Institute Davos 2018-01-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/papers/vol035/pdf/v035a02.pdf