The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis

The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis

Treatment of non-small cell lung cancer (NSCLC) is based on histological analysis and molecular profiling of targetable driver oncogenes. Therapeutic responses are further defined by the landscape of passenger mutations, or loss of tumor suppressor genes. We report here a thorough study to address t...

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Bibliographic Details
Main Authors: Jenni Lahtela, Barun Pradhan, Katja Närhi, Annabrita Hemmes, Merja Särkioja, Panu E. Kovanen, Arthur Brown, Emmy W. Verschuren
Format: Article
Language:English
Published: The Company of Biologists 2015-04-01
Series:Disease Models & Mechanisms
Subjects:
EPHA3
EPH receptor A3
GEMM
Adenocarcinoma
Lung morphogenesis
Online Access:http://dmm.biologists.org/content/8/4/393

Internet

http://dmm.biologists.org/content/8/4/393

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