Activation of Bone Marrow-Derived Cells Angiotensin (Ang) II Type 1 Receptor by Ang II Promotes Atherosclerotic Plaque Vulnerability

Activation of Bone Marrow-Derived Cells Angiotensin (Ang) II Type 1 Receptor by Ang II Promotes Atherosclerotic Plaque Vulnerability

Angiotensin (Ang) II triggers vulnerable atherosclerotic plaque development. Bone marrow (BM)-derived cells are key players in atherogenesis but whether Ang II induces plaque vulnerability directly through Ang II type 1 receptor (AT1R) activation on these cells remains to be clarified. In the presen...

Full description

Bibliographic Details
Main Authors: Maxime Pellegrin, Karima Bouzourène, Jean-François Aubert, Aimable Nahimana, Michel A. Duchosal, Lucia Mazzolai
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
atherosclerosis
vulnerable plaque
Angiotensin II
inflammation
2-kidney, 1-clip ApoE−/− mice
bone marrow transplantation
Online Access:http://www.mdpi.com/1422-0067/19/9/2621

Internet

http://www.mdpi.com/1422-0067/19/9/2621

Similar Items