Lack of IκBNS promotes cholate-containing high-fat diet-induced inflammation and atherogenesis in low-density lipoprotein (LDL) receptor-deficient mice

Lack of IκBNS promotes cholate-containing high-fat diet-induced inflammation and atherogenesis in low-density lipoprotein (LDL) receptor-deficient mice

Background: IκBNS, a nuclear IκB protein, regulates a subset of Toll-like receptor (TLR) dependent genes. A cholate-containing high-fat diet (HFD(CA(+))) induces TLR4 mediated early inflammatory response. The present study aims to clarify that the lack of IκBNS promotes atherogenesis in low-density...

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Bibliographic Details
Main Authors: Kenichi Kitamura, Kikuo Isoda, Koji Akita, Katsutoshi Miyosawa, Tomoyasu Kadoguchi, Kazunori Shimada, Hiroyuki Daida
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:International Journal of Cardiology: Heart & Vasculature
Online Access:http://www.sciencedirect.com/science/article/pii/S2352906719300399

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http://www.sciencedirect.com/science/article/pii/S2352906719300399

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