D1 Dopamine Receptor Activation Induces Neuronal eEF2 Pathway-Dependent Protein Synthesis

Dopamine, alongside other neuromodulators, defines brain and neuronal states, inter alia through regulation of global and local mRNA translation. Yet, the signaling pathways underlying the effects of dopamine on mRNA translation and psychiatric disorders are not clear. In order to examine the molecu...

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Bibliographic Details
Main Authors: Orit David, Iliana Barrera, Nathaniel Gould, Shunit Gal-Ben-Ari, Kobi Rosenblum
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
ERK
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00067/full