PPARγ and PPARα synergize to induce robust browning of white fat in vivo

PPARγ and PPARα synergize to induce robust browning of white fat in vivo

Objective: Peroxisome proliferator-activated receptors (PPARs) are key transcription factors that regulate adipose development and function, and the conversion of white into brown-like adipocytes. Here we investigated whether PPARα and PPARγ activation synergize to induce the browning of white fat....

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Bibliographic Details
Main Authors: Tobias Kroon, Matthew Harms, Stefanie Maurer, Laurianne Bonnet, Ida Alexandersson, Anna Lindblom, Andrea Ahnmark, Daniel Nilsson, Peter Gennemark, Gavin O'Mahony, Victoria Osinski, Coleen McNamara, Jeremie Boucher
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Metabolism
Subjects:
Brown adipocytes
Beige adipocytes
Thermogenesis
UCP1
FGF21
PPAR
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820300363

Internet

http://www.sciencedirect.com/science/article/pii/S2212877820300363

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