The Differential Diagnosis of Discrepant Thyroid Function Tests: Insistent Pitfalls and Updated Flow-Chart Based on a Long-Standing Experience

The Differential Diagnosis of Discrepant Thyroid Function Tests: Insistent Pitfalls and Updated Flow-Chart Based on a Long-Standing Experience

Background: Discrepant thyroid function tests (TFTs) are typical of inappropriate secretion of TSH (IST), a rare entity encompassing TSH-secreting adenomas (TSHoma) and Resistance to Thyroid Hormone (RTHβ) due to THRB mutations. The differential diagnosis remains a clinical challenge in most of the...

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Bibliographic Details
Main Authors: Irene Campi, Danila Covelli, Carla Moran, Laura Fugazzola, Chiara Cacciatore, Fabio Orlandi, Gabriella Gallone, Krishna Chatterjee, Paolo Beck-Peccoz, Luca Persani
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Endocrinology
Subjects:
hyperthyroidism
pituitary adenoma
resistance to thyroid hormone
thyroid hormone
thyrotropin (TSH)
immuno-assay
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00432/full

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https://www.frontiersin.org/article/10.3389/fendo.2020.00432/full

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