Uroplakin Ib Gene Transcription in Urothelial Tumor Cells Is Regulated by CpG Methylation
Uroplakin Ib is a structural protein on the surface of urothelial cells. Levels of uroplakin Ib mRNA are dramatically reduced or absent in many transitional cell carcinomas, but the molecular mechanisms responsible remain undetermined. Previously, we showed that loss of uroplakin Ib expression corr...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2005-12-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558605800466 |