Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma

Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma

Abstract Background Cutaneous melanoma is the deadliest skin cancer, with an increasing incidence and mortality rate. Currently, staging of patients with primary melanoma is performed using histological biomarkers such as tumor thickness and ulceration. As disruption of the epigenomic landscape is r...

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Bibliographic Details
Main Authors: Jasper Wouters, Miguel Vizoso, Anna Martinez-Cardus, F. Javier Carmona, Olivier Govaere, Teresa Laguna, Jesuchristopher Joseph, Peter Dynoodt, Claudia Aura, Mona Foth, Roy Cloots, Karin van den Hurk, Balazs Balint, Ian G. Murphy, Enda W. McDermott, Kieran Sheahan, Karin Jirström, Bjorn Nodin, Girish Mallya-Udupi, Joost J. van den Oord, William M. Gallagher, Manel Esteller
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Medicine
Subjects:
Melanoma/skin cancers
Molecular diagnosis and prognosis
Molecular markers of metastasis and progression
Tumor staging
Correlation of clinical and molecular markers
Online Access:http://link.springer.com/article/10.1186/s12916-017-0851-3

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http://link.springer.com/article/10.1186/s12916-017-0851-3

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