Role of microRNA-33a in regulating the expression of PD-1 in lung adenocarcinoma

Role of microRNA-33a in regulating the expression of PD-1 in lung adenocarcinoma

Abstract Background MiRNAs are vital in functioning as either oncogenes or tumor suppressors in the cell cycle. Target transcripts for immune checkpoint molecules such as PD-1/PD-L1 and (programmed cell death-1/its ligand and cytotoxic T-lymphocyte antigen 4) have proven to be beneficial against sev...

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Bibliographic Details
Main Authors: Laura Boldrini, Mirella Giordano, Cristina Niccoli, Franca Melfi, Marco Lucchi, Alfredo Mussi, Gabriella Fontanini
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Cancer Cell International
Subjects:
miR-33a
PD-1
Lung adenocarcinoma
Online Access:http://link.springer.com/article/10.1186/s12935-017-0474-y

Internet

http://link.springer.com/article/10.1186/s12935-017-0474-y

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