The initial step in human immunodeficiency virus type 1 GagProPol processing can be regulated by reversible oxidation.

<h4>Background</h4>Maturation of human immunodeficiency virus type 1 (HIV-1) occurs upon activation of HIV-1 protease embedded within GagProPol precursors and cleavage of Gag and GagProPol polyproteins. Although reversible oxidation can regulate mature protease activity as well as retrov...

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Bibliographic Details
Main Authors: Sarah I Daniels, David A Davis, Erin E Soule, Stephen J Stahl, Irene R Tebbs, Paul Wingfield, Robert Yarchoan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21042582/pdf/?tool=EBI