Stereotactic radiosurgery optimization with hippocampal-sparing in patients treated for brain metastases

Background and purpose: Cranial irradiation is associated with significant neurocognitive sequelae, secondary to radiation-induced damage to hippocampal cells. It has been shown that hippocampal-sparing (HS) leads to modest benefit in neurocognitive function in patients with brain metastases, but fu...

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Bibliographic Details
Main Authors: Laura Burgess, Vimoj Nair, Julie Gratton, Janice Doody, Lynn Chang, Shawn Malone
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Physics and Imaging in Radiation Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405631621000130