Muscle Twitch Kinetics Are Dependent on Muscle Group, Disease State, and Age in Duchenne Muscular Dystrophy Mouse Models

Muscle Twitch Kinetics Are Dependent on Muscle Group, Disease State, and Age in Duchenne Muscular Dystrophy Mouse Models

Duchenne muscular dystrophy (DMD) is an X-linked disorder caused by the lack of functional dystrophin protein. In muscular dystrophy preclinical research, it is pertinent to analyze the force of the muscles affected by the disease to assess pathology and potential effectiveness of therapeutic interv...

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Bibliographic Details
Main Authors: Kyra K. Peczkowski, Neha Rastogi, Jeovanna Lowe, Kyle T. Floyd, Eric J. Schultz, Tallib Karaze, Jonathan P. Davis, Jill A. Rafael-Fortney, Paul M. L. Janssen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Physiology
Subjects:
skeletal muscle
muscular dystrophies
contraction
relaxation
age
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.568909/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.568909/full

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