The Drosophila TIPE family member Sigmar interacts with the Ste20-like kinase Misshapen and modulates JNK signaling, cytoskeletal remodeling and autophagy

The Drosophila TIPE family member Sigmar interacts with the Ste20-like kinase Misshapen and modulates JNK signaling, cytoskeletal remodeling and autophagy

TNFAIP8 and other mammalian TIPE family proteins have attracted increased interest due to their associations with disease-related processes including oncogenic transformation, metastasis, and inflammation. The molecular and cellular functions of TIPE family proteins are still not well understood. He...

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Bibliographic Details
Main Authors: Suganthi Chittaranjan, Jing Xu, Michael Kuzyk, Harpreet K. Dullat, James Wilton, Lindsay DeVorkin, Chandra Lebovitz, Gregg B. Morin, Marco A. Marra, Sharon M. Gorski
Format: Article
Language:English
Published: The Company of Biologists 2015-07-01
Series:Biology Open
Subjects:
Eiger
Msn
Autophagy
Cytoskeleton
TNFAIP8
TIPE
Online Access:http://bio.biologists.org/content/4/5/672

Internet

http://bio.biologists.org/content/4/5/672

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