Immunohistochemistry and fluorescence in-situ hybridization study for detection of anaplastic lymphoma kinase gene rearrangement in nonsmall cell lung carcinoma

Immunohistochemistry and fluorescence in-situ hybridization study for detection of anaplastic lymphoma kinase gene rearrangement in nonsmall cell lung carcinoma

Patients and methods Testing for Anaplastic Lymphoma Kinas (ALK) rearrangement is now recommended for selection of lung cancer patients targeted for Tyrosine-kinase inhibitors (Crizotimib). We used Fluorescence in situ hybridization (FISH) compared with Immunohistochemical (IHC) staining method to e...

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Bibliographic Details
Main Authors: Mohamed Hantera, Ibrahim S Ibrahim, Amira Y Abdelnaby, Ayman El Saka, Heba F Harras
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Egyptian Journal of Chest Disease and Tuberculosis
Subjects:
anaplastic lymphoma kinase gene
fluorescence in-situ hybridization
immunohistochemistry
nonsmall cell lung carcinoma
Online Access:http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2018;volume=67;issue=2;spage=182;epage=190;aulast=Hantera

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http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2018;volume=67;issue=2;spage=182;epage=190;aulast=Hantera

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