Dissecting Long-Term Glucose Metabolism Identifies New Susceptibility Period for Metabolic Dysfunction in Aged Mice.

Dissecting Long-Term Glucose Metabolism Identifies New Susceptibility Period for Metabolic Dysfunction in Aged Mice.

Metabolic disorders, like diabetes and obesity, are pathogenic outcomes of imbalance in glucose metabolism. Nutrient excess and mitochondrial imbalance are implicated in dysfunctional glucose metabolism with age. We used conplastic mouse strains with defined mitochondrial DNA (mtDNA) mutations on a...

Full description

Bibliographic Details
Main Authors: Anuradha Chauhan, Heike Weiss, Franziska Koch, Saleh M Ibrahim, Julio Vera, Olaf Wolkenhauer, Markus Tiedge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4634931?pdf=render

Internet

http://europepmc.org/articles/PMC4634931?pdf=render

Similar Items