A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein.

A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein.

Apolipoprotein B-containing lipoproteins (B-lps) are essential for the transport of hydrophobic dietary and endogenous lipids through the circulation in vertebrates. Zebrafish embryos produce large numbers of B-lps in the yolk syncytial layer (YSL) to move lipids from yolk to growing tissues. Disrup...

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Bibliographic Details
Main Authors: Meredith H Wilson, Sujith Rajan, Aidan Danoff, Richard J White, Monica R Hensley, Vanessa H Quinlivan, Rosario Recacha, James H Thierer, Frederick J Tan, Elisabeth M Busch-Nentwich, Lloyd Ruddock, M Mahmood Hussain, Steven A Farber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008941

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https://doi.org/10.1371/journal.pgen.1008941

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