The Protective Effects of Shengmai Formula Against Myocardial Injury Induced by Ultrafine Particulate Matter Exposure and Myocardial Ischemia are Mediated by the PI3K/AKT/p38 MAPK/Nrf2 Pathway

The Protective Effects of Shengmai Formula Against Myocardial Injury Induced by Ultrafine Particulate Matter Exposure and Myocardial Ischemia are Mediated by the PI3K/AKT/p38 MAPK/Nrf2 Pathway

Background and Purpose: Ultrafine particulate matter (UFPM) induces oxidative stress (OS) and is considered to be a risk factor of myocardial ischemia (MI). Shengmai formula (SMF) is a traditional Chinese medicine with antioxidant properties and has been used to treat cardiovascular diseases for a l...

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Bibliographic Details
Main Authors: Lina Chen, Yuan Guo, Shuiqing Qu, Kai Li, Ting Yang, Yuanmin Yang, Zhongyuan Zheng, Hui Liu, Xi Wang, Shuoqiu Deng, Yu Zhang, Xiaoxin Zhu, Yujie Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
Shengmai formula
myocardial injury
ultrafine particulate matter
oxidative stress
PI3K/AKT/p38 MAPK/Nrf2 pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.619311/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.619311/full

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