Metal-induced stabilization and activation of plasmid replication initiator RepB
Initiation of plasmid rolling circle replication is catalyzed by a plasmid-encoded Rep protein that performs a Tyr- and metal-dependent site-specific cleavage of one DNA strand within the double-strand origin of replication. The crystal structure of RepB, the initiator protein of the streptococcal p...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-09-01
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Series: | Frontiers in Molecular Biosciences |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmolb.2016.00056/full |