The Wanderings of Gut-Derived IgA Plasma Cells: Impact on Systemic Immune Responses

Humoral immunity is mainly mediated by a B cell population highly specialized to synthesize and secrete large quantities of antibodies – the antibody-secreting cells (ASC). In the gastrointestinal environment, a mixture of foreign antigens from the diet, commensal microbiota as well as occasional ha...

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Bibliographic Details
Main Authors: Selina J. Keppler, Marie Christine Goess, Julia M. Heinze
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.670290/full