Immunologic response to vaccine challenge in pregnant PTPN22 R620W carriers and non-carriers.

Influenza infection is a significant cause of respiratory morbidity among pregnant women. Seasonal influenza vaccination engages innate immune receptors to promote protective immunity. A coding polymorphism (R620W) in PTPN22 imparts elevated risk for human infection and autoimmune disease, predispos...

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Bibliographic Details
Main Authors: Shelly H Tien, Juliet N Crabtree, Heather L Gray, Erik J Peterson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5517002?pdf=render