The Melatonergic System in Mood and Anxiety Disorders and the Role of Agomelatine: Implications for Clinical Practice

The Melatonergic System in Mood and Anxiety Disorders and the Role of Agomelatine: Implications for Clinical Practice

Melatonin exerts its actions through membrane MT1/MT2 melatonin receptors, which belong to the super family of G-protein-coupled receptors consisting of the typical seven transmembrane domains. MT1 and MT2 receptors are expressed in various tissues of the body either as single ones or together. A gr...

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Bibliographic Details
Main Authors: Domenico De Berardis, Stefano Marini, Michele Fornaro, Venkataramanujam Srinivasan, Felice Iasevoli, Carmine Tomasetti, Alessandro Valchera, Giampaolo Perna, Maria-Antonia Quera-Salva, Giovanni Martinotti, Massimo di Giannantonio
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:International Journal of Molecular Sciences
Subjects:
melatonin
melatonergic receptors
serotonin
dopamine
noradrenaline
agomelatine
major depression
anxiety
Online Access:http://www.mdpi.com/1422-0067/14/6/12458

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http://www.mdpi.com/1422-0067/14/6/12458

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